A TEST OF EFFECTIVENESS OF LEMONGRASS EXTRACT (Cymbopogon citratus) IN WOUND HEALING PROCESS ON
WHITE MICE
By:
Maharuni Nurqadriasti Djuddawi
K1A214007
ABSTRACT
The wound is defined as an injury to the part of the body, that is, when the skin and underlying tissue lose its tissue continuity. Lemongrass is one of the grass plants often used as a medicine. In traditional medicine, lemongrass has broad indications as analgesic, antiseptic, antiemetic, antitussive,antirheumatic, anticonvulsant, as well as gastrointestinal and neurological treatments. Lemongrass is also used as an antibacterial, anti-inflammatory, and antioxidants that can affect the wound healing process. This study aims to determine the effectiveness of lemongrass extract (Cymbopogon citratus) 30%, 60 and 80% compared with control negative and positive group in incised wound on white mice.
This research is a true experimental research with post-test design only control group using complete randomized design (RAL). This research used 25 white mice divided into 5 groups: 30% lemongrass extract, 60% lemongrass extract, 80% lemongrass extract, negative control (Aquades) and positive control (Bioplacenton).
Result of analysis of Shapiro Wilk normality test data got significant value in each group show p> 0,05 (normal data distribution). Levene's Test homogeneity test was obtained p = 0,730 (p> 0,05) it showed that homogeneous data, then continued with One Way ANOVA test showed, with p> 0,05 (0,881). Then it can be said that H0 failed to reject.
Based on the research that has been done, it can be concluded that there is no difference in effectiveness of lemongrass extract (Cymbopogon citratus) 30%, 60% and 80% compared with negative control groups and positive control.
Keywords: Lemongrass extract, Wound healing, Incised wound.